Increasing demands on component properties are leading to the development of high-performance materials, where conventional production methods are reaching their limits from an economic and ecological point of view. In recent years, two technologies have been developed that stand out from conventional machining processes, particularly in the machining of hard-to-machine materials such as the titanium alloy Ti 6Al 4V. Ultrasonic-assisted machining makes it possible to reduce cutting forces and increase tool life. The cryogenic minimum quantity lubrication prevents the occurrence of high machining temperatures and allows higher cutting volumes with the same tool life. As a logical consequence, the influence of ultrasonic-assisted milling and grinding processes in combination with cryogenic minimum quantity lubrication on the machinability of higher or high-strength materials such as Ti 6Al 4V and the glass ceramic material Zerodur is to be investigated in this project. The focus of the project is on the investigation of the cutting forces, the tool life, the metal removal rate as well as the influence on the micro and macro conditions of the workpiece surface. The aim is to identify the effects of the technology overlay and to develop concrete applications.