Johannes Kremheller, M.Sc.

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Research Interests
Teaching
Publications

Articles in Peer-Reviewed International Journals

Kremheller, J., Brandstaeter, S., Schrefler, B. A., Wall W. A. (2021): Validation and parameter optimization of a hybrid embedded/homogenized solid tumor perfusion model, accepted, International Journal for Numerical Methods in Biomedical Engineering, DOI

Steinbrecher, I., Mayr, M., Grill, M. J., Kremheller, J., Meier, C., Popp, A. (2020): A mortar-type finite element approach for embedding 1D beams into 3D solid volumes, Computational Mechanics, DOI

Wirthl B.*, Kremheller J.*, Schrefler B.A., Wall W. A. (2020), Extension of a multiphase tumour growth model to study nanoparticle delivery to solid tumours, PLOS ONE, 15(2):e0228443, DOI (*co-first authorship)

Kremheller, J., Vuong, A.-T., Schrefler, B. A., Wall, W. A. (2019): An approach for vascular tumor growth based on a hybrid embedded/homogenized treatment of the vasculature within a multiphase porous medium model, International Journal for Numerical Methods in Biomedical Engineering, 35:e3253, DOI

Kremheller, J., Vuong, A.-T., Yoshihara, L., Wall, W. A., Schrefler, B. A. (2018): A monolithic multiphase porous medium framework for (a-)vascular tumor growth, Computer Methods in Applied Mechanics and Engineering, 340:657-683, DOI

Hesse, S. H., Leidinger, L. F., Kremheller, J., Lukaszewicz, D., Duddeck, F. (2018): Shape optimization with the level-set-method using local volume constraints, Structural and Multidisciplinary Optimization, 57:115-130, DOI

Seitz, A., Farah, P., Kremheller, J., Wohlmuth, B.I., Wall, W.A., Popp, A. (2016): Isogeometric dual mortar methods for computational contact mechanics, Computer Methods in Applied Mechanics and Engineering, 301:259-280, DOI

International Conference Contributions with Abstract

J. Kremheller, A.-T. Vuong, B. A. Schrefler, W. A. Wall, A Hybrid Embedded/Homogenized In-Silico Approach for Tumor Growth and Mass Transport Inside Tumors, 14th WCCM & ECCOMAS Congress 2020, Virtual Congress, January 11 - 15, 2021

W. A. Wall, J. Kremheller, A.-T. Vuong, B. A. Schrefler. A Multiscale Method for Embedding One-dimensional Fluid or Solid Models in Three-dimensional Continua with Application to Vascular Tumor Growth, 15th U.S. National Congress on Computational Mechanics, Austin, Texas, United States, July 28 - August 1, 2019

J. Kremheller, A.-T. Vuong, W. A. Wall, B. A. Schrefler. An embedded multiscale method for vascular tumor growth, Gordon Research Conference on Physical Science of Cancer, Galveston, United States, February 10 - 15, 2019

Raffaella Santagiuliana, Johannes Kremheller, Pietro Mascheroni, Lena Yoshihara, Wolfgang A. Wall, Paolo Decuzzi, Bernhard A. Schrefler. Advances of a General Model for Tumor Growth and Drug Delivery, 13th World Congress in Computational Mechanics - WCCMXIII, New York, United States, July 23 - 27, 2018

J. Kremheller, A.-T. Vuong, L. Yoshihara, W. A. Wall, B. A. Schrefler. A novel five-phase model for (a-)vascular tumor growth within a flexible computational framework, 6th International Conference on Computational Mechanics - ECCM2018, Glasgow, United Kingdom, June 11 - 15, 2018

Presentations and invited talks

J. Kremheller, B. Wirthl, A.-T. Vuong, W. A. Wall, B. A. Schrefler, An embedded multiscale method for vascular tumor growth and drug delivery, Houston Methodist Research Institute, Houston, 18 February, 2019

J. Kremheller, A.-T. Vuong, L. Yoshihara, W. A. Wall, B. A. Schrefler. A flexible in-silico framework for modeling (a-)vascular tumor growth, Focal Period Workshop on Advanced Computational Modeling for Tumor Growth Prediction, TUM Institute for Advanced Study, Garching bei München, 24 - 25 September, 2018

Supervised Student Projects
  • Modeling of drug delivery and hyperthermia treatment in a multiphase tumor growth model, Master's Thesis, Barbara Wirthl, 2018
  • Investigations of the influence of anisotropy on (a-)vascular tumor growth with a computational model, term paper, 2019
  • Output Monitoring Routines for Parameter Studies in a Finite Element Tumour Growth Model, Bachelor's Thesis, 2019 (co-supervised with Barbara Wirthl)
  • Global Sensitivity Analysis of a Multiphase Model for Avascular Tumor Growth, Master's Thesis (Physics), 2020 (co-supervised with Jonas Nitzler)
  • Visualization of three-dimensional vascular tumor growth, Visualization Techniques in Computational Mechanics, 2020
  • A study of pharmacokinetics and pharmacodynamics in a multiphase tumor growth model, MSE research internships, 2020 (co-supervised with Barbara Wirthl)
  • Modelling of blood vessel compression in a computational tumor growth model, Master's Thesis, 2020 (co-supervised with Barbara Wirthl)
  • Heterogeneous Multiscale Method in Markovian event-based models - With applications in tumor modeling, Master's Thesis (in progress, in co-operation with Martin Kronbichler and Prof. Engblom, Uppsala University)
  • Visualization of three-dimensional blood vessel networks inside a tumor, Visualization Techniques in Computational Mechanics, 2020
  • An anisotropic poro-mechanical formulation for lung tissue, Master's Thesis (co-supervised with Carolin Geitner)
  • Modelling of gas exchange and blood flow in lung tissue, Master's Thesis (co-supervised with Carolin Geitner)

Education

since 2017  Research Associate at the Institute for Computational Mechanics (Lehrstuhl für Numerische Mechanik), TUM, Germany

2016 Master of Science (M.Sc.), Mechanical Engineering, TUM, Germany